The massive dimensionality of genomic data combined with the lack of knowledge of gene function have been major barriers to the use of Artificial Intelligence (AI) in genomics. The number of population sequencing initiatives is rapidly increasing. As these large genomic datasets grow and become more widely available, the prospect of using artificial intelligence to gain insights from this data becomes more tangible and the use of such technology becomes even more important. In this session we review the current state and future directions of using AI with genomic data.